美國(guó)BD公司Purified Mouse anti-TAZ抗體Clone M2-616
美國(guó)BD公司Purified Mouse anti-TAZ抗體Clone M2-616
美國(guó)BD公司Purified Mouse anti-TAZ抗體Clone M2-616
規(guī)格
0.1 mg
貨號(hào)
560235
目錄價(jià)
¥ 5,543.00
Brand
BD Pharmingen™
Alternative Name
WWTR1
Concentration
0.5 mg/ml
Isotype
Mouse BALB/c IgG2b, κ
Reactivity
Human (QC Testing) Mouse (Tested in Development)
Application
Western blot (Routinely Tested)
Bioimaging (Tested During Development)
Immunogen
Human TAZ Recombinant Protein
Storage Buffer
Aqueous buffered solution containing ≤0.09% sodium azide.
詳細(xì)說(shuō)明：
Taz is a 49-kDa transcriptional co-activator with a PDZ-binding motif and is regulated by binding with 14-3-3 proteins. It plays a key role in differentiation of mesenchymal stem cells into either osteoblasts or adipocytes via interactions with key transcription factors Runx2 and PPAR γ . More recently, Taz was found to be a component of an E3 ubiquitin ligase involved in ubiquitin-dependent substrate proteolysis by mediating its interaction with the F-box protein β -Trcp. Therefore, Taz has dual functions of regulating protein degradation and transcription.
Format
Purified
| Cat No. | Description | Size | |
|---|---|---|---|
| 611449 | HeLa Cell Lysate RUO | 500 µg |
|
| 554656 | Stain Buffer (FBS) RUO | 500 mL |
|
| 554655 | Fixation Buffer RUO | 100 mL |
|
| 554723 | Perm/Wash Buffer RUO | 100 mL |
|
| 554002 | HRP Goat Anti-Mouse Ig RUO | 1 mL |
|
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.
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